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- Tel: 858.663.9055
- Email: info@nsjbio.com
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CD86 is a receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. Isoform 2 interferes with the formation of CD86 clusters, and thus acts as a negative regulator of T-cell activation. [UniProt]
Optimal dilution of the CD86 antibody should be determined by the researcher.
1. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Tris buffer with 1mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 min.
Recombinant human full-length protein was used as the immunogen for the CD86 antibody.
Store the CD86 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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