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Home >> Antibodies >> CD79b Antibody [Discontinued, view alternative antibodies]

CD79b Antibody [Discontinued, view alternative antibodies] [clone IGB/1844] (V3956)

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  Catalog No Formulation Size Price (USD)  
Image V3956-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 100 ug 519
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V3956-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 20 ug 229
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V3956SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 519
Microvalidated
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Analysis of HuProt(TM) microarray containing more than 19,000 full-length human proteins using CD79b antibody (clone IGB/1844). These results demonstrate the foremost specificity of the IGB/1844 mAb. Z- and S- score: The Z-score represents the strength of a signal that an antibody (in combination with a fluorescently-tagged anti-IgG secondary Ab) produces when binding to a particular protein on the HuProt(TM) array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If the targets on the HuProt(TM) are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-scores. The S-score therefore represents the relative target specificity of an Ab to its intended target.
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Analysis of HuProt(TM) microarray containing more than 19,000 full-length human proteins using CD79b antibody (clone IGB/1844). These results demonstrate the foremost specificity of the IGB/1844 mAb.
Z- and S- score: The Z-score represents the strength of a signal that an antibody (in combination with a fluorescently-tagged anti-IgG secondary Ab) produces when binding to a particular protein on the HuProt(TM) array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If the targets on the HuProt(TM) are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-scores. The S-score therefore represents the relative target specificity of an Ab to its intended target.
SDS-PAGE analysis of purified, BSA-free CD79b antibody (clone IGB/1844) as confirmation of integrity and purity.
Availability Discontinued
Species Reactivity Human
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG1, kappa
Clone Name IGB/1844
Purity Protein G affinity chromatography
UniProt P40259
Localization Cell surface
Applications ELISA : 2-4ug/ml (order BSA/azide-free format)
Limitations This CD79b antibody is available for research use only.
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Description

CD79 (also designated Ig alpha/Ig beta) is a heterodimer composed of alpha chains, designated CD79A or MB-1, and beta chains, designated CD79B or B29. The B cell antigen receptor complex (BCR) is formed by the association of CD79 with a membrane immunoglobulin, such as IgM or IgD. The membrane immunoglobulins IgM and IgD achieve surface expression and antigen presentation function in response to CD79 association. The cytoplasmic tails of both CD79A and CD79B contain an ITAM (immuno-receptor tyrosine-based activation) motif, which acts to initiate the BCR signaling reactions by binding to and activating tyrosine kinases.

Application Notes

Optimal dilution of the CD79b antibody should be determined by the researcher.

Immunogen

A portion of amino acids 29-159 was used as the immunogen for the CD79b antibody.

Storage

Store the CD79b antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Related Products

   1.   View all CD79b antibodies

   2.   View all human protein microarray validated antibodies

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