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- Email: info@nsjbio.com
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The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis.
Titration of the CD70 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 72-101 from the human protein was used as the immunogen for this CD70 antibody.
Aliquot the CD70 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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