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Home >> Antibodies >> CD70 Antibody

CD70 Antibody (F44122)

  Catalog No Formulation Size Price (USD)  
Image F44122-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F44122-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
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CD70 antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue.
CD70 antibody western blot analysis in NCI-H460 lysate
Availability 1-3 business days
Species Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt P32970
Applications Western blot : 1:1000
IHC (Paraffin) : 1:10-1:50
Limitations This CD70 antibody is available for research use only.
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Description

The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis.

Application Notes

Titration of the CD70 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 72-101 from the human protein was used as the immunogen for this CD70 antibody.

Storage

Aliquot the CD70 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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