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Home >> Antibodies >> CD64 Antibody / FCGR1A

CD64 Antibody / FCGR1A [clone 10.1] (V7768)

  Catalog No Formulation Size Price (USD)  
Image V7768-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 100 ug 519
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V7768-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 20 ug 229
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V7768SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 519
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Flow cytometry staining of monocyte-gated human PBM cells with CD64 antibody (clone 10.1); Gray=isotype control, Red= CD64 antibody.
Flow cytometry staining of human U937 cells with CD64 antibody (clone 10.1); Gray=isotype control, Red= CD64 antibody.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG1, kappa
Clone Name 10.1
Purity Protein G affinity chromatography
UniProt P12314
Applications Flow cytometry : 1-2ug/million cells
Limitations This CD64 antibody is available for research use only.
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Description

Three different classes of IgG Fc receptors have been described: Fc stimulation. CD64 plays a putative role in the initiation of cell-mediated cytotoxicity. Thus far, three genes encoding four distinct CD64 transcripts have been described. CD64 has been shown to associate with signal transducing subunit of the high affinity IgE receptor. Src family kinases Hck and Lyn show increased kinase activity and will co-immunoprecipitate with CD64 subsequent to receptor cross linking.

Application Notes

Optimal dilution of the CD64 antibody should be determined by the researcher.

Immunogen

Rheumatoid synovial fluid cells and human monocytes were used as the immunogen for the CD64 antibody.

Storage

Store the CD64 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

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