- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
CD50 Antibody / ICAM-3 [clone CG106] (V7853)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
V7853-100UG | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide | 100 ug | 519 | |
|
|
V7853-20UG | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide | 20 ug | 229 | |
|
|
V7853SAF-100UG | 1 mg/ml in 1X PBS; BSA free, sodium azide free | 100 ug | 519 |
|
| Availability | 1-3 business days |
| Species Reactivity | Human |
| Format | Purified |
| Clonality | Monoclonal (mouse origin) |
| Isotype | Mouse IgG2a, kappa |
| Clone Name | CG106 |
| Purity | Protein G affinity chromatography |
| UniProt | P32942 |
| Localization | Cell surface |
| Applications | Blocks binding of CD11a/LFA-1 to CD50/ICAM-3 (order BSA/azide-free format) : Flow cytometry : 1-2ug/10^6 cells in 0.1ml Immunofluorescence : 1-2ug/ml |
| Limitations | This CD50 antibody is available for research use only. |
|
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Recognizes the D1 domain of an N-glycosylated glycoprotein of 120kDa with intra-chain disulfide bonds, identified as CD50 or ICAM-3 (Leucocyte Workshop VI). CD50 is the major ligand for LFA-1 (CD11a/CD18) and may have signaling role to increase adhesion. It is expressed on thymocytes and T lymphocytes and is resistant to treatment with phosphatidylinositol (PI) phospholipase C.
Optimal dilution of the CD50 antibody should be determined by the researcher.
Stimulated human leukocytes were used as the immunogen for the CD50 antibody.
Store the CD50 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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