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Home >> Antibodies >> CD209 Antibody / DC-SIGN

CD209 Antibody / DC-SIGN [clone C209/6774] (V9406)

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  Catalog No Formulation Size Price (USD)  
Image V9406-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 100 ug 519
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V9406-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 20 ug 229
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V9406SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 519
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SDS-PAGE analysis of purified, BSA-free CD209 antibody (clone C209/6774) as confirmation of integrity and purity.
SDS-PAGE analysis of purified, BSA-free CD209 antibody (clone C209/6774) as confirmation of integrity and purity.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG1, kappa
Clone Name C209/6774
Purity Protein A/G affinity
UniProt Q9NNX6
Localization Cell surface and secreted
Applications Flow cytometry : 1-2ug/million cells
Limitations This CD209 antibody is available for research use only.
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Description

DC-SIGN/CD209 is a transmembrane receptor that is expressed on the surface of dendritic cells and macrophages. It is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens ranging from parasites to viruses. The protein is organized into three distinct domains: an N-terminal transmembrane domain, a tandem-repeat neck domain and C-type lectin carbohydrate recognition domain. The extracellular region consisting of the C-type lectin and neck domains has a dual function as a pathogen recognition receptor and a cell adhesion receptor by binding carbohydrate ligands on the surface of microbes and endogenous cells. The neck region is important for homo-oligomerization, which allows the receptor to bind multivalent ligands with high avidity.

Application Notes

Optimal dilution of the CD209 antibody should be determined by the researcher.

Immunogen

A recombinant human DC-SIGN/CD209 protein fragment was used as the immunogen for the CD209 antibody.

Storage

Aliquot the CD209 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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