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Home >> Antibodies >> CD2 Antibody

CD2 Antibody [clone LFA2/8681R] (V4641)

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  Catalog No Formulation Size Price (USD)  
Image V4641-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 100 ug 519
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V4641-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 20 ug 229
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V4641SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 519
Microvalidated Recrabbitmono
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IHC staining of FFPE human spleen tissue with CD2 antibody (clone LFA2/8681R). Inset: PBS used in place of primary Ab (secondary Ab negative control). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
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IHC staining of FFPE human spleen tissue with CD2 antibody (clone LFA2/8681R). Inset: PBS used in place of primary Ab (secondary Ab negative control). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
SDS-PAGE analysis of purified, BSA-free CD2 antibody (clone LFA2/8681R) as confirmation of integrity and purity.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Recombinant Rabbit Monoclonal
Isotype Rabbit IgG, kappa
Clone Name LFA2/8681R
Purity Protein A/G affinity
UniProt P06729
Localization Cell surface
Applications Immunohistochemistry (FFPE) : 1-2ug/ml for 30 min at RT
Limitations This CD2 antibody is available for research use only.
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Description

CD2 is mainly present on the surface of mature T cells and NK cell membranes, while B cells are usually not expressed. It can be used to label the diagnosis and study of normal T cells and their associated tumors, such as pre-t cell lymphoma, marginal T cell lymphoma and anaplastic cell lymphoma. CD2 antibody is useful for identification of precursor and mature T-cell lymphomas. Aberrant loss of CD2 in T-cell lymphomas may help to distinguish them from reactive T-cell proliferations.

Application Notes

Optimal dilution of the CD2 antibody should be determined by the researcher.

Immunogen

A recombinant fragment corresponding to the N-terminal of human CD2 protein was used as the immunogen for the CD2 antibody.

Storage

Aliquot the CD2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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