CD1b Antibody RIV12 | V2028 NSJ Bioreagents

	Catalog No	Formulation	Size	Price (USD)
	V2028-100UG	0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide	100 ug	519
Formulation
	V2028-20UG	0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide	20 ug	229
Formulation
	V2028SAF-100UG	1 mg/ml in 1X PBS; BSA free, sodium azide free	100 ug	519
Formulation

Bulk quote request

FACS staining of human PBMCs using CD1b antibody (RIV12).

Species Reactivity	Human
Format	Purified
Clonality	Monoclonal (mouse origin)
Isotype	Mouse IgG1, kappa
Clone Name	RIV12
Purity	Protein G affinity chromatography
Buffer	1X PBS, pH 7.4
Gene ID	910
Localization	Cell surface, cytoplasmic
Applications	ELISA (order BSA/sodium azide-free format for coating) : Flow cytometry : 0.5-1ug/10^6 cells Immunofluorescence : 0.5-1ug/ml
Limitations	This CD1b antibody is available for research use only.
	Review this product on BioCompare and get a $20 Amazon gift card

Description

This antibody recognizes CD1b, a 44kDa type I glycoprotein associated with beta2-microglobulin. It is expressed on dendritic cells, Langerhans cells, thymocytes, and T acute lymphoblastic leukemia cells. The CD1 multigene family encodes five forms of the CD1 T-cell surface glycoprotein in human, designated CD1A, 1B, 1C, 1D and 1E. CD1, a type 1 membrane protein, has structural similarity to the MHC class I antigen and has been shown to present lipid antigens for recognition by T lymphocytes. Constitutive endocytosis of CD1b molecules and the differential sorting of MHC class II from lysosomes separate peptide- and lipid antigen-presenting molecules during dendritic cell maturation. It is also expressed in interdigitating cells.

Application Notes

The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the CD1b antibody to be titered up or down for optimal performance.