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- Tel: 858.663.9055
- Email: info@nsjbio.com
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ITGAX is the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles.
Titration of the CD11c antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 1119-1145 from the human protein was used as the immunogen for this CD11c antibody.
Aliquot the CD11c antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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