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Home >> Antibodies >> CCL2 Antibody / MCP1

CCL2 Antibody / MCP1 (RQ4664)

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  Catalog No Formulation Size Price (USD)  
Image RQ4664 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Western blot testing of rat pancreas with CCL2 antibody at 0.5ug/ml. Expected molecular weight ~11 kDa (precursor), ~9 kDa (mature).
Western blot testing of rat pancreas with CCL2 antibody at 0.5ug/ml. Expected molecular weight ~11 kDa (precursor), ~9 kDa (mature).
Availability 1-3 business days
Species Reactivity Rat
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity purified
Buffer Lyophilized from 1X PBS with 2% Trehalose
UniProt P14844
Applications Western blot : 0.5-1ug/ml
ELISA (Capture) : 1-5ug/ml (recombinant rat protein)
Limitations This CCL2 antibody is available for research use only.
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Description

Monocyte chemoattractant protein-1 (MCP-1), a member of the chemokine (chemotactic cytokine) family, is a potent monocyte agonist that is upregulated by oxidized lipids. MCP-1 is also known as CCL2, SCYA2, MCAF. MCAF is a member of family of factors involved in immune and inflammatory responses. The amino acid sequence deduced from the nucleotide sequence reveals the primary structure of the MCAF precursor to be composed of a putative signal peptide sequence of 23 amino acid residues and a mature MCAF sequence of 76 amino acid residues. MCP-1 plays a unique and crucial role in the initiation of atherosclerosis and may provide a new therapeutic target in this disorder. Human MCP-1 is a 8.7KDa non-glycoprotein, consisting of 99 amino acids in precursor form and 76 amino acids in mature form.

Application Notes

Optimal dilution of the CCL2 antibody should be determined by the researcher.

Immunogen

Amino acids Q24-R96 from the rat protein were used as the immunogen for the CCL2 antibody.

Storage

After reconstitution, the CCL2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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