- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
Cathepsin L/V/K/H Antibody [clone AACD-3] (RQ5182)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
RQ5182 | Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA | 100 ul | 429 |
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| Availability | 1-2 weeks |
| Species Reactivity | Human, Mouse, Rat |
| Format | Purified |
| Clonality | Rabbit Monoclonal |
| Isotype | Rabbit IgG |
| Clone Name | AACD-3 |
| Purity | Affinity purified |
| UniProt | P07711 |
| Applications | Western blot : 1:500-1:2000 |
| Limitations | This Cathepsin L/V/K/H antibody is available for research use only. |
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Cathepsins are proteases (enzymes that degrade proteins) found in all animals as well as other organisms. There are approximately a dozen members of this family, which are distinguished by their structure, catalytic mechanism, and which proteins they cleave. Most of the members become activated at the low pH found in lysosomes. Thus, the activity of this family lies almost entirely within those organelles. There are, however, exceptions such as cathepsin K, which works extracellularly after secretion by osteoclasts in bone resorption. Cathepsins have a vital role in mammalian cellular turnover. [Wiki]
Optimal dilution of the Cathepsin L/V/K/H antibody should be determined by the researcher.
A synthetic peptide common to human Cathepsin L/V/K/H was used as the immunogen for the Cathepsin L/V/K/H antibody.
Store the Cathepsin L/V/K/H antibody at -20oC.
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