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Home >> Antibodies >> Cathepsin D Antibody / CTSD

Cathepsin D Antibody / CTSD [clone CP-D13] (R30012)

  Catalog No Formulation Size Price (USD)  
Image R30012 0.5mg/ml with 1% BSA and 0.01% sodium azide if reconstituted with 0.2ml sterile 1X PBS 100 ug 429
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IHC testing of FFPE human intestinal cancer tissue with Cathepsin D antibody. HIER: steamed with pH6 citrate buffer, HRP-staining.
IHC testing of FFPE human breast cancer tissue with Cathepsin D antibody. HIER: steamed with pH6 citrate buffer, HRP-staining.
IHC testing of FFPE human lung cancer tissue with Cathepsin D antibody. HIER: steamed with pH6 citrate buffer, HRP-staining.
Availability 1-3 business days
Species Reactivity Human
Format Ascites
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG2a
Clone Name CP-D13
Purity Ascites
Gene ID 1509
Localization Cytoplasmic
Applications Western blot : 0.5-1ug/ml
IHC (FFPE) : 1-2ug/ml
Limitations This Cathepsin D antibody is available for research use only.
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Description

Cathepsin D is one of the lysosomal proteinases. It is ubiquitously expressed and is involved in proteolytic degradation, cell invasion, and apoptosis. Cathepsin D is mapped to chromosome 11. The amino acid sequence predicted from the cDNA sequence shows that human cathepsin D consists of 412 amino acids with 20 and 44 amino acids in a pre- and a prosegment, respectively.

Application Notes

Titration of the Cathepsin D antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

Human liver cathepsin D was used as the immunogen for this Cathepsin D antibody.

Storage

After reconstitution, the Cathepsin D antibody can be stored at 4oC to -20oC. For long-term, aliquot and store at -20oC. Avoid repeated freeze/thaws.

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