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- Tel: 858.663.9055
- Email: info@nsjbio.com
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Calponin is a basic ~34-kD protein first isolated from chicken gizzard and bovine aorta. This gene is mapped to 19p13.2. It is specifically expressed in smooth muscle and binds calmodulin, actin, and tropomyosin. It is able to inhibit the ATPase activity of myosin and is though to play a role in smooth muscle contraction. Calponin is a smooth muscle specific, actin-, tropomyosin- and calmodulin-binding protein though to be involved in some way in the regulation or modulation of contraction.
The stated application concentrations are suggested starting amounts. Titration of the Calponin antibody may be required due to differences in protocols and secondary/substrate sensitivity.
An amino acid sequence from the C-terminus of human Calponin (EPAHNHHAHNYYNSA) was used as the immunogen for this Calponin antibody.
After reconstitution, the Calponin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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