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- Email: info@nsjbio.com
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Cell adhesion molecule 1 is a protein that, in humans, is encoded by the CADM1 gene. This gene is also known as IGSF4, SYNCAM or TSLC1, and it is mapped to 11q23.3. It functions as a homophilic cell adhesion molecule at the synapse. Expression of the isolated cytoplasmic tail of CADM1 in neurons inhibited synapse assembly. Conversely, expression of full-length protein in non-neuronal cells induced synapse formation by cocultured hippocampal neurons with normal release properties. It has been shown to interact with EPB41L3.
The stated application concentrations are suggested starting amounts. Titration of the CADM1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
An amino acid sequence from the N-terminus of human SynCAM/CADM1 (VIQLLNPNRQTIYFRDFRPL) was used as the immunogen for this CADM1 antibody (100% homologous in human, mouse and rat).
After reconstitution, the CADM1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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