- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
C4A Antibody / Complement C4A [clone AFHB-3] (RQ5301)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
RQ5301 | Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA | 100 ul | 429 |
|
| Availability | 1-2 weeks |
| Species Reactivity | Human |
| Format | Purified |
| Clonality | Rabbit Monoclonal |
| Isotype | Rabbit IgG |
| Clone Name | AFHB-3 |
| Purity | Affinity purified |
| UniProt | P0C0L4 |
| Applications | Western blot : 1:500-1:2000 |
| Limitations | This C4A antibody is available for research use only. |
|
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This gene encodes the acidic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain is cleaved to release C4 anaphylatoxin, an antimicrobial peptide and a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus and type I diabetes mellitus. [RefSeq]
Optimal dilution of the C4A antibody should be determined by the researcher.
A synthetic peptide specific to human C4A / Complement C4A was used as the immunogen for the C4A antibody.
Store the C4A antibody at -20oC.
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