- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
c-Kit Antibody / SCFR / CD117 [clone C117/8399R] (V5051)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
V5051-100UG | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide | 100 ug | 519 | |
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V5051-20UG | 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide | 20 ug | 229 | |
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V5051SAF-100UG | 1 mg/ml in 1X PBS; BSA free, sodium azide free | 100 ug | 519 |
| Availability | 1-3 business days |
| Species Reactivity | Human |
| Format | Purified |
| Clonality | Recombinant Rabbit Monoclonal |
| Isotype | Rabbit IgG, kappa |
| Clone Name | C117/8399R |
| Purity | Protein A/G affinity |
| UniProt | P10721 |
| Localization | Cell surface, Cytoplasm |
| Applications | ELISA : 2-4ug/ml (Order BSA-free format for coating) Immunohistochemistry (FFPE) : 1-2ug/ml for 30 min at RT |
| Limitations | This c-Kit antibody is available for research use only. |
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This mAb recognizes a protein of 145kDa, identified as CD117/p145kit. It is found on a wide variety of tumor cells including follicular and papillary carcinoma of thyroid, adenocarcinomas from endometrium, lung, ovary, pancreas, and breast as well as malignant melanoma, endodermal sinus tumor, and small cell carcinoma. However, anti-CD117 has been particularly useful in differentiating gastrointestinal stromal tumors from Kaposi s sarcoma, tumors of smooth muscle origin, fibromatosis, and neural tumors of the GI tract. Anti-CD117 is also useful in recognizing myeloblasts in bone marrow biopsy and clot section.
Optimal dilution of the c-Kit antibody should be determined by the researcher.
A recombinant partial protein sequence (within amino acids 50-250) from the human protein was used as the immunogen for the c-Kit antibody.
Aliquot the c-Kit antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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