- Tel: 858.663.9055
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- Tel: 858.663.9055
- Email: info@nsjbio.com
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The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement.
Titration of the BTK antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 209-239 from the human protein was used as the immunogen for this BTK antibody.
Aliquot the BTK antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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