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Home >> Antibodies >> Blood Group Lewis y Antibody

Blood Group Lewis y Antibody [clone LWY/9243R] (V5378)

  Catalog No Formulation Size Price (USD)  
Image V5378-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 100 ug 539
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V5378-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 20 ug 249
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V5378SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 539
Microvalidated Recrabbitmono
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IHC staining of FFPE human stomach tissue with Blood Group Lewis y antibody (clone LWY/9243R). Inset: PBS used in place of primary Ab (secondary Ab negative control).
SDS-PAGE analysis of purified, BSA-free Blood Group Lewis y antibody (clone LWY/9243R) as confirmation of integrity and purity.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Recombinant Rabbit Monoclonal
Isotype Rabbit IgG, kappa
Clone Name LWY/9243R
Purity Protein A/G affinity
Localization Cell membrane, Cytoplasm, Extracellular
Applications Immunohistochemistry (FFPE) : 1-2ug/ml
Limitations This Blood Group Lewis y antibody is available for research use only.
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Description

This antibody recognizes a carbohydrate epitope present on tumor-associated Lewis Y antigen (Fucalpha1-2Galbeta1-4/3[Fucalpha1-3/4]GlcNAcbeta-). Lewis Y is expressed in large bowel tumors and colorectal carcinomas. It may be useful in the classification of human renal and bladder tumors. The Lewis Y antigen has been evaluated as a clinical marker for the diagnosis and prognosis of cholangiocarcinoma, hepatocellular carcinoma and breast cancer.

Application Notes

Optimal dilution of the Blood Group Lewis y antibody should be determined by the researcher.

Immunogen

H3396 cultured line established from a metastasis of a human breast adenocarcinoma was used as the immunogen for the Blood Group Lewis y antibody.

Storage

Aliquot the Blood Group Lewis y antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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