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- Tel: 858.663.9055
- Email: info@nsjbio.com
Beta-defensin 1, is a protein that in humans is encoded by the DEFB1 gene. DEFB1 belongs to the defensin family. Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. The DEFB1 gene spans more than 7 kb and includes a large 6,962-bp intron. By 2-color fluorescence in situ hybridization on both metaphase chromosomes and released chromatin fiber, the DEFB1 gene is mapped to 8p23.2-p23.1, within 100 to 150 kb of the gene for human neutrophil defensin-alpha-1. DEFB1 may augment neonatal host defenses through antimicrobial effects or prime the adaptive immune system at mucosal surfaces.
The stated application concentrations are suggested starting amounts. Titration of the beta Defensin 1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
An amino acid sequence from the C-terminus of human beta Defensin 1 (FTKIQGTCYRGKAKCCK) was used as the immunogen for this beta Defensin 1 antibody.
After reconstitution, the beta Defensin 1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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