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Home >> Antibodies >> BDNF Antibody

BDNF Antibody (R30184)

  Catalog No Formulation Size Price (USD)  
Image R30184 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Western blot testing of BDNF antibody and Lane 1: rat brain; 2: mouse brain; 3: MCF-7; Predicted size: 28KD; Observed size: 37KD
Availability 1-3 business days
Species Reactivity Human, Mouse, Rat
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity
Buffer Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal
UniProt P23560
Applications Western blot : 0.5-1ug/ml
Limitations This BDNF antibody is available for research use only.
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Description

Brain derived neurotrophic factor (BDNF) is a member of the neurotrophin family of growth factors that includes NGF, NT3, and NT4. BDNF is a prosurvival factor induced by cortical neurons that is necessary for survival of striatal neurons in the brain. BDNF is expressed within peripheral ganglia and is not restricted to neuronal target fields. BDNF has been purified and shown to reduce the amount of naturally occurring neuronal cell death in portions of the peripheral nervous system.

Application Notes

The stated application concentrations are suggested starting points. Titration of the BDNF antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

An amino acid sequence from the N-terminal of human BDNF (HSDPARRGELSVCDSISEWV) was used as the immunogen for this BDNF antibody.

Storage

After reconstitution, the BDNF antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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