- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
BCL-6 Antibody [clone 305CT16.3.3] (F40298)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
F40298-0.4ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.4 ml | 399 | |
|
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F40298-0.08ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.08 ml | 185 |
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| Availability | 1-3 business days |
| Species Reactivity | Human |
| Format | Purified |
| Clonality | Monoclonal (mouse origin) |
| Isotype | Mouse IgG1, k |
| Clone Name | 305CT16.3.3 |
| Purity | Purified |
| UniProt | P41182 |
| Applications | Western blot : 1:100-1:250 |
| Limitations | This BCL-6 antibody is available for research use only. |
|
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The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of START-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene.
Titration of the BCL-6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 676-704 from the human protein was used as the immunogen for this BCL-6 antibody.
Aliquot the BCL-6 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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