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Home >> Antibodies >> BCL-2 Antibody

BCL-2 Antibody (F47585)

  Catalog No Formulation Size Price (USD)  
Image F47585-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F47585-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
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BCL-2 antibody pre-incubated without (Lane 1) and with (2) blocking peptide in 293 lysate
Availability 1-3 business days
Species Reactivity Human
Predicted Reactivity Bovine, Hamster, Mouse, Rat
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt P10415
Applications Western blot : 1:1000
Limitations This BCL-2 antibody is available for research use only.
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Description

This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends. [provided by RefSeq].

Application Notes

Titration of the BCL-2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 87-116 from the human protein was used as the immunogen for this BCL-2 antibody.

Storage

Aliquot the BCL-2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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