- Tel: 858.663.9055
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Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
ATP1A3 Antibody / Sodium Potassium ATPase Antibody detects ATPase Na K transporting subunit alpha 3, a catalytic alpha subunit of the sodium potassium ATPase membrane pump responsible for maintaining cellular ion gradients. ATP1A3 uses energy from ATP hydrolysis to exchange intracellular sodium ions for extracellular potassium ions, helping establish the electrochemical gradients required for membrane potential regulation. The alpha 3 isoform is highly enriched in neurons, where rapid restoration of ion balance is essential for normal electrical activity and cellular function.
The sodium potassium ATPase complex is a transmembrane enzyme composed of catalytic and regulatory subunits that work together to maintain ion homeostasis. ATP1A3 contributes to neuronal excitability, signal transmission and recovery following action potentials by supporting sodium and potassium balance across the plasma membrane. ATP1A3 Antibody is commonly used by researchers studying neuronal membrane biology, ion transport pathways, ATP-dependent transport mechanisms and nervous system function.
Research involving ATP1A3 has provided important insight into neurological function and disease-associated changes in ion pump activity. Mutations affecting ATP1A3 function have been investigated in neurological disorders involving abnormal neuronal signaling, movement regulation and brain development. Because neurons require precise control of membrane potential and ionic gradients, ATP1A3 remains an important target in studies of neuronal physiology, synaptic activity and neurobiology.
ATP1A3 expression is commonly examined in neural tissues and specialized cell populations to better understand sodium potassium ATPase regulation and membrane transporter activity. Studies of ATP-dependent ion pumps help define how cells maintain homeostasis, respond to changes in activity and preserve proper signaling conditions. Analysis of ATP1A3 also supports broader research into membrane protein biology, energy-dependent transport and cellular communication.
ATP1A3 Antibody applications include detection of ATPase alpha 3 expression, localization and regulation in biological samples using techniques such as Western blot, immunohistochemistry, immunofluorescence and related protein analysis methods. NSJ Bioreagents provides ATP1A3 Antibody / Sodium Potassium ATPase Antibody for researchers studying neuronal ion transport, sodium potassium ATPase function and nervous system regulation.
ATP1A3 Antibody detects a neuronal sodium potassium ATPase involved in ion transport, membrane potential regulation and nervous system signaling, making it a useful marker for research areas featured in our Neuroscience Antibodies page.
Optimal dilution of the ATP1A3 Antibody / Sodium Potassium ATPase Antibody should be determined by the researcher.
E. coli-derived recombinant human ATPase Na K transporting subunit alpha 3 protein (amino acids D24-D583) was used as the immunogen for the ATP1A3 Antibody.
After reconstitution, the ATP1A3 Antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Na K ATPase Alpha 3 Antibody, Sodium Potassium Transporting ATPase Alpha 3 Antibody, ATPase Alpha 3 Antibody, Sodium Pump Antibody, Neuronal Ion Pump Antibody, ATP1A3 Protein Antibody
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