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Home >> Antibodies >> ABCD1 Antibody

ABCD1 Antibody (F40661)

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  Catalog No Formulation Size Price (USD)  
Image F40661-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F40661-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
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ABCD1 antibody western blot analysis in human 1) 293/T17 and 2) HL-60 lysate. Predicted molecular weight ~83 kDa.
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ABCD1 antibody western blot analysis in human 1) 293/T17 and 2) HL-60 lysate. Predicted molecular weight ~83 kDa.
ABCD1 antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human hepatocarcinoma.
ABCD1 antibody flow cytometric analysis of HL-60 cells (right histogram) compared to a negative control (left histogram). FITC-conjugated goat-anti-rabbit secondary Ab was used for the analysis.
Availability 1-3 business days
Species Reactivity Human
Predicted Reactivity Mouse
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt P33897
Applications Western blot : 1:1000
IHC (Paraffin) : 1:50-1:100
Flow Cytometry : 1:10-1:50
Limitations This ABCD1 antibody is available for research use only.
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  • Applications : WB, ELISA (peptide)
    Reactivity : Human

Description

ABCD1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein is likely involved in the peroxisomal transport or catabolism of very long chain fatty acids. Defects in this gene have been identified as the underlying cause of adrenoleukodystrophy, an X-chromosome recessively inherited demyelinating disorder of the nervous system.

Application Notes

Titration of the ABCD1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 257-285 from the human protein was used as the immunogen for this ABCD1 antibody.

Storage

Aliquot the ABCD1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Related Products

   1.   View all rabbit isotype control antibodies

   2.   View all ABCD1 antibodies

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