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Home >> Antibodies >> C-C chemokine receptor type 2 Antibody / CCR2

C-C chemokine receptor type 2 Antibody / CCR2 (RQ6938)

  Catalog No Formulation Size Price (USD)  
Image RQ6938 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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IHC staining of FFPE human lymphoma tissue with C-C chemokine receptor type 2 antibody. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.
IHC staining of FFPE human cervical cancer tissue with C-C chemokine receptor type 2 antibody. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.
IHC staining of FFPE human placental tissue with C-C chemokine receptor type 2 antibody. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.
Western blot testing of human Jurkat cell lysate with C-C chemokine receptor type 2 antibody. Predicted molecular weight ~42 kDa.
Availability 1-3 business days
Species Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity purified
Buffer Lyophilized from 1X PBS with 2% Trehalose
UniProt P41597
Applications Western blot : 0.5-1 ug/ml
Immunohistochemistry (FFPE) : 2-5ug/ml
Direct ELISA : 0.1-0.5ug/ml
Limitations This C-C chemokine receptor type 2 antibody is available for research use only.
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Description

C-C chemokine receptor type 2 (CCR2 or CD192 (cluster of differentiation 192) is a protein that in humans is encoded by the CCR2 gene. It is mapped to 3p21.31. The protein encoded by this gene is a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The encoded protein mediates agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This protein can also be a coreceptor with CD4 for HIV-1 infection.

Application Notes

Optimal dilution of the C-C chemokine receptor type 2 antibody should be determined by the researcher.

Immunogen

Recombinant human protein (amino acids R6-L45) was used as the immunogen for the C-C chemokine receptor type 2 antibody.

Storage

After reconstitution, the C-C chemokine receptor type 2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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